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The EcoRI−DNA Complex as a Model for Investigating Protein−DNA Interactions by Atomic Force Microscopy

✍ Scribed by Sorel, Isabelle; Piétrement, Olivier; Hamon, Loïc; Baconnais, Sonia; Le Cam, Eric; Pastré, David

Book ID
115468442
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
438 KB
Volume
45
Category
Article
ISSN
0006-2960

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## Abstract The tumor suppressor p53 interacts with the redox copper protein Azurin (AZ) forming a complex which is of some relevance in biomedicine and cancer therapy. To obtain information on the spatial organization of this complex when it is immobilized on a substrate, we have used tapping mode