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The early course of affective and cognitive symptoms in de novo patients with Parkinson’s disease

✍ Scribed by Spalletta, Gianfranco; Robinson, Robert G.; Cravello, Luca; Pontieri, Francesco E.; Pierantozzi, Mariangela; Stefani, Alessandro; Long, Jeffrey D.; Caltagirone, Carlo; Assogna, Francesca

Book ID
121852025
Publisher
Springer
Year
2014
Tongue
English
Weight
217 KB
Volume
261
Category
Article
ISSN
0340-5354

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## Abstract Little is known about the course of depressive symptoms in Parkinson's disease (PD). We studied the course of clinically significant depressive symptoms using data from two clinical trials that followed 413 early, untreated PD subjects for 12 to 18 months. We measured depressive symptom