Histone deacetylase activity in conjunct
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Deborah M. Wallace; Thomas G. Cotter
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 904 KB
## Abstract Apaf‐1 and the cysteine proteases known as caspases are genes central to the intrinsic apoptotic pathway in the retina. Previously, we have shown that histone deacetylase (HDAC) activity regulates Apaf‐1 expression in the retina. In this study, we unravel the detailed molecular mechanis