𝔖 Bobbio Scriptorium
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The E1A proteins of adenovirus render infected cells susceptible to TNF cytolysis


Book ID
123514532
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
169 KB
Volume
1
Category
Article
ISSN
1043-4666

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TNF is a key inflammatory cytokine with antiviral properties. Human adenoviruses encode several intracellular proteins that mediate the effects of TNF. Expression of the adenovirus immediate early EIA proteins induces viral genes and a host of cellular genes, drives Go cells into S-phase, and induce