The expression of variant mRNAs encoding isoforms of fibroblast growth factor receptor (FGFR)I with either 2 or 3 Ig-like loops in the extracellular domain was investigated in human breast tissues and cell lines using a polymerase chain reaction amplification method. Almost all tissues contained bot
The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor
β Scribed by Steegmaler, Martin; Levinovitz, Agneta; Isenmann, Sandra; Borges, Eric; Lenter, Martin; Kocher, Hans P.; Kleuser, Beate; Vestweber, Dletmar
- Book ID
- 109791178
- Publisher
- Nature Publishing Group
- Year
- 1995
- Tongue
- English
- Weight
- 642 KB
- Volume
- 373
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/373615a0
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De novo bile acid synthesis in the liver needs to be tightly regulated in order to maintain optimal bile flow and prevent cholestasis. In the liver, fibroblast growth factor 19 (FGF19) regulates bile acid synthesis by down-regulating messenger RNA levels of cytochrome P450 7A1 (CYP7A1). FGF19 acts t