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The dynamics of neurological disease: integrating computational, experimental and clinical neuroscience

✍ Scribed by Stephen Coombes; John R. Terry


Book ID
115184156
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
67 KB
Volume
36
Category
Article
ISSN
0953-816X

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Parkinson's disease (PD) is characterized by motor and nonmotor (cognitive and limbic) deficits. The motor signs of PD include hypokinetic signs such as akinesia/bradykinesia, rigidity and loss of normal postural reflexes, and hyperkinetic signs such as tremor. Dopamine depletion in the striatum is