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The dual-specificity MAP kinase phosphatases: critical roles in development and cancer

โœ Scribed by Bermudez, O.; Pages, G.; Gimond, C.


Book ID
118244270
Publisher
The American Physiological Society
Year
2010
Tongue
English
Weight
292 KB
Volume
299
Category
Article
ISSN
0363-6143

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## Abstract Inactivation of tumor suppressor genes through deletion, mutation and epigenetic silencing has been shown to occur in cancer. In our study, we combined DNA demethylation and histone deacetylation inhibition treatments with suppression subtraction hybridization (SSH) and cDNA microarrays