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The dual angiogenesis/metastasis inhibitor PG545 inhibits growth factor-induced cell migration and invasion in vitro and tumor growth in vivo of ovarian cancer cells

✍ Scribed by S. Giri; B. Winterhoff; J. Maguire; A. Teoman; K. Dredge; V. Shridhar


Book ID
113963905
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
81 KB
Volume
125
Category
Article
ISSN
0090-8258

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## Abstract Berberine has been shown to have anti‐carcinogenic effects. Since p53 is the most commonly mutated tumor suppressor gene, and a lack of functional p53 is associated with an increased risk of cancer development, we examined the effects of berberine on p53‐positive and p53‐deficient non‐s