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The dual activity of pyruvate kinase type M2 from chromatin extracts of neoplastic cells

โœ Scribed by Jan Ignacak; Maria Barbara Stachurska


Book ID
117733749
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
431 KB
Volume
134
Category
Article
ISSN
1096-4959

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The dual activity of pyruvate kinase typ
โœ Jan Ignacak; Maria Barbara Stachurska ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 431 KB

Pyruvate kinase type M(2) from Morris hepatoma 7777 tumour cell nuclei and cytosol, in contrast to types L and M(2) from nuclei and cytosol of normal rat liver, shows the histone H(1) kinase activity. Moreover, in the presence of L-cysteine and without ADP it converts 2-phosphoenolpyruvate (PEP) to