The Drosophila cell shape regulator c-Jun N-terminal kinase also functions as a stress-activated protein kinase
✍ Scribed by José A. Botella; Ian A. Baines; Daniel D. Williams; Deborah C.I. Goberdhan; Chris G. Proud; Clive Wilson
- Book ID
- 117672986
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 190 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0965-1748
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Recently identified c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase are activated by stimuli of various cellular stresses, cytokines, and growth factors. Strong activation of JNK was reported in the regenerating liver, implicating JNK in growth stimulation of hepatocytes. Howe
Glial cells in the mammalian CNS are subject to environmental stress resulting from a variety of neuropathological conditions. In this study, we have examined the activation of a stress signal responsive kinase, i.e., stress-activated protein kinase (SAPK) or cJun N-terminal kinase (JNK), in primary