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The dopamine agonist cabergoline provides neuroprotection by activation of the glutathione system and scavenging free radicals

โœ Scribed by Michiyo Yoshioka; Ken-ichi Tanaka; Ikuko Miyazaki; Naoko Fujita; Youichirou Higashi; Masato Asanuma; Norio Ogawa


Book ID
117363966
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
254 KB
Volume
43
Category
Article
ISSN
0168-0102

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โœ Kamogawa, Erisa; Sueishi, Yoshimi ๐Ÿ“‚ Article ๐Ÿ“… 2014 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 517 KB

Edaravone (3-methyl-1-phenyl-2-pyrazoline-5-one) is a neuroprotective drug that has been used for brain ischemia injury treatment. Because its activity is speculated to be due to free radical scavenging activity, we carried out a quantitative determination of edaravone's free radical scavenging acti