The DNA vaccine website. http://www.genweb.com/Dnavax/
✍ Scribed by Thomas Valère
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 91 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1099-498X
No coin nor oath required. For personal study only.
✦ Synopsis
DNA-mediated immunization has been referred to as the `third vaccine revolution'. Often, scientists are unfamiliar with these new developments.
Essentially, plasmid DNA harboring genes to be expressed can be transferred directly into various tissues of an organism using simple methods involving needle injection or particle bombardment. Such plasmid vectors containing the elements required for expression in eukaryotic organisms allow the in situ expression of antigenic proteins. From this starting point, many applications can be envisioned relating either to vaccine design and development, or with regard to basic research in immunology.