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The DNA sequence of cosmid 14-5 from chromosome XIV reveals 21 open reading frames including a novel gene encoding a globin-like domain

✍ Scribed by Pandolfo, Davide; de Antoni, Anna; Lanfranchi, Gerolamo; Valle, Giorgio

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 487 KB
Volume: 12
Category: Article
ISSN: 0749-503X
DOI: 10.1002/(sici)1097-0061(199609)12:10b<1071::aid-yea4>3.0.co;2-s

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✦ Synopsis

In this paper is described the DNA sequence of cosmid 14-5 from chromosome XIV of Succizuronz~~ces crrevisiue. The sequence is 38 855 bases long and contains 21 open reading frames (ORFs) plus three internal ORFs. Six ORFs correspond to known yeast genes (SLA2, ZWFI, B L H l , K E M . SIN4 and URE2); two other ORFs had already been sequenced because they are adjacent to known genes: the remaining 12 ORFs are novel genes. Of these, one O R F (N1142) is particularly interesting since it shows a significant similarity to mammalian globin. Another ORF (N1254) displays two zinc finger motifs as well as a DNAJ motif.

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