The distribution of various water soluble radioactive metalloporphyrins in tumor bearing mice

✍ Scribed by P. Hambright; R. Fawwaz; P. Valk; J. McRae; A.J. Bearden

• Book ID: 104105985
• Publisher: Elsevier Science
• Year: 1975
• Weight: 353 KB
• Volume: 5
• Category: Article
• ISSN: 0006-3061
• DOI: 10.1016/s0006-3061(00)80224-0

✦ Synopsis

The distribution of a variety of water soluble ' "Pd and 64Cu porphyrins were studied in mice bearing three types of tumors. While the metalloporphyrins are found to have an affinity for neoplastic tissue, substantial extra-tumor concentrations are also noted. Although this limits their value as specific tumor imaging agents. their use in Iocalized therapy is discussed_ We rhonk the USAEC, Contract No. AT-f40-I)-4047 for partial financial support to P-H.