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The distribution of melanin-concentrating hormone-like immunoreactivity in the central nervous system of rat, guinea-pig and man

✍ Scribed by K Sekiya; MA Ghatei; PWJ Burnet; SR Bloom


Book ID
118397872
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
57 KB
Volume
18
Category
Article
ISSN
0167-0115

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Urocortin was recently cloned from the rat midbrain. Urocortin is a member of the corticotropin releasing factor (CRF) peptide family and shows 45% sequence identity to CRF and 63% sequence identity to urotensin. It binds with a high affinity to CRF 1 and CRF 2 receptors, resulting in the stimulatio