The distribution of fitness effects of new mutations

✍ Scribed by Eyre-Walker, Adam; Keightley, Peter D.

• Book ID: 109952607
• Publisher: Nature Publishing Group
• Year: 2007
• Tongue: English
• Weight: 330 KB
• Volume: 8
• Category: Article
• ISSN: 1471-0056
• DOI: 10.1038/nrg2146

✦ Synopsis

Muller's ratchet

The process by which a genome with little or no recombination degenerates owing to the stochastic loss of the allelic class with fewest deleterious mutations.