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The distribution of cholecystokinin immunoreactivity in the central nervous system of the rat as determined by radioimmunoassay

✍ Scribed by Margery C. Beinfeld; Dieter K. Meyer; Robert L. Eskay; Robert T. Jensen; Michael J. Brownstein


Book ID
118866410
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
397 KB
Volume
212
Category
Article
ISSN
0006-8993

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Urocortin was recently cloned from the rat midbrain. Urocortin is a member of the corticotropin releasing factor (CRF) peptide family and shows 45% sequence identity to CRF and 63% sequence identity to urotensin. It binds with a high affinity to CRF 1 and CRF 2 receptors, resulting in the stimulatio