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The disposition kinetics of diazepam in pregnant women at parturition

โœ Scribed by R. G. Moore; W. G. McBride


Publisher
Springer
Year
1978
Tongue
English
Weight
896 KB
Volume
13
Category
Article
ISSN
0031-6970

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The effects of ibuprofen on maternal phenytoin pharmacokinetics and fetal phenytoin acquisition were investigated in 19-day gestation Sprague-Dawley rats. A 5 mg kg-' bolus injection of I4C-phenytoin was given with and without (control) pretreatment with 12.5 mg kg-' of ibuprofen. Maternal plasma an