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The “Dispensable” Portion of RAG2 Is Necessary for Efficient V-to-DJ Rearrangement during B and T Cell Development

✍ Scribed by Hong-Erh Liang; Lih-Yun Hsu; Dragana Cado; Lindsay G. Cowell; Garnett Kelsoe; Mark S. Schlissel

Book ID
117723291
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
944 KB
Volume
17
Category
Article
ISSN
1074-7613

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## Abstract Nod2 belongs to the nucleotide‐binding domain leucine‐rich repeat family of proteins and senses bacterial cell wall components to initiate innate immune responses against various pathogens. Recently, it has been reported that T‐cell‐intrinsic expression of Nod2 promotes host defense aga