The discovery of thyroid autoimmunity
β Scribed by Noel R. Rose
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 238 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0167-5699
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The Role Of Epigenetic Mechanisms In Autoimmune Disease Is Only Now Starting To Become Clear. Understanding These Mechanisms, Their Effect On Cellular Function And The Role Of Environmental Factors Is Vital To Determining How To Manage These Often Debilitating And Fatal Diseases. drawing On The Res
## Abstract Thyroid function and ultrasonographically determined thyroid volume were studied in nine pregnant women with diagnosed autoimmune thyroid disease at regular intervals during pregnancy and two months after delivery. The results were compared to the findings in ten healthy pregnant women.
Experimental autoimmune thyroid disease (EAT) can be induced experimentally in mice following immunization with mouse thyroglobulin (mTg) and the adjuvants lipopolysaccharide (LPS) or complete Freund's adjuvant (CFA). EAT can also be transferred to naive recipients by CD4 + T cells from mTg-primed m