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The discovery of the microphthalmia locus and its gene, Mitf

✍ Scribed by Heinz Arnheiter

Book ID
118074874
Publisher
Wiley (Blackwell Publishing)
Year
2010
Tongue
English
Weight
113 KB
Volume
23
Category
Article
ISSN
1755-1471

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The murine microphthalmia gene (Mitf) encodes a basic helix-loop-helix transcription factor thought to regulate transcription of genes encoding proteins of the pigmentation pathway. It may promote pigment cell survival and development. The protein encoded by Mitf appears to be critical for eye devel