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The discovery of new isocyanide-based multi-component reactions

✍ Scribed by Alexander Dömling

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
147 KB
Volume
4
Category
Article
ISSN
1367-5931

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✦ Synopsis

Multi-component reactions are finding increasing use in the discovery process of new drugs and agrochemicals. Some years ago they were considered as highly exotic types of organic reactions. Recently, many groups have realized that the field of multi-component reactions is full of new opportunities. These comprise fast and efficient production of small-molecular-weight compound libraries, highly atom-economic chemistry, very large chemical libraries, improvements in total synthesis, and applications in bioconjugate chemistry, as well as in related fields (e.g. chemical biology).

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