✦ LIBER ✦

The discovery of L-699,392, a novel potent and orally active leukotriene D4 receptor antagonist

✍ Scribed by M. Labelle; M. Belley; E. Champion; R. Gordon; K. Hoogsteen; T.R. Jones; Y. Leblanc; A. Lord; M. McAuliffe; C. McFarlane; P. Masson; K.M. Metters; D. Nicoll-Griffith; N. Ouimet; H. Piechuta; C. Rochette; N. Sawyer; Y.B. Xiang; J. Yergey; A.W. Ford-Hutchinson; C.B. Pickett; R.J. Zamboni; R.N. Young

Book ID: 108038778
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 311 KB
Volume: 4
Category: Article
ISSN: 0960-894X
DOI: 10.1016/0960-894x(94)80017-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of MK-0476, a potent and orall

Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction

✍ M. Labelle; M. Belley; Y. Gareau; J.Y. Gauthier; D. Guay; R. Gordon; S.G. Grossm 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 325 KB

The discovery of CP-96,021 and CP-96,486

The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.

✍ A. Marfat; R. Chambers; J. Cheng; K. Cooper; D. Damon; J. Delehunt; J. Eggler; H 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 343 KB

Discovery of novel, potent, selective, a

Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core

✍ Dong-Ming Shen; Edward J. Brady; Mari R. Candelore; Qing Dallas-Yang; Victor D.- 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 461 KB

A novel class of 1,3,5-pyrazoles has been discovered as potent human glucagon receptor antagonists. Notably, compound 26 is orally bioavailable in several preclinical species and shows selectivity towards cardiac ion channels, other family B receptors such hGIP and hGLP1, and a large panel of enzyme

ChemInform Abstract: Discovery of Novel,

ChemInform Abstract: Discovery of Novel, Potent, Selective, and Orally Active Human Glucagon Receptor Antagonists Containing a Pyrazole Core.

✍ Dong-Ming Shen; et al. et al. 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

Stereospecific HPLC method for the quant

Stereospecific HPLC method for the quantitation of the enantiomers of MK-0571, a potent leukotriene D4 receptor antagonist, in biological specimens

✍ Ling L. Lee; Anthony G. Zacchei 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 704 KB

Synthesis and Structure–Activity Relatio

Synthesis and Structure–Activity Relationship of the Isoindolinyl Benzisoxazolpiperidines as Potent, Selective, and Orally Active Human Dopamine D4 Receptor Antagonists

✍ James A. Hendrix; Stephen J. Shimshock; Gregory M. Shutske; John D. Tomer IV; Ke 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB 👁 1 views