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The different (sur)faces of Rap1p

✍ Scribed by B. Piña; J. Fernández-Larrea; N. García-Reyero; F.-Z. Idrissi

Publisher: Springer
Year: 2003
Tongue: English
Weight: 357 KB
Volume: 268
Category: Article
ISSN: 1617-4615
DOI: 10.1007/s00438-002-0801-3

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## Abstract Tuberous sclerosis complex (TSC) is an autosomal dominant syndrome in which affected individuals develop nervous system abnormalities that might reflect astrocyte dysfunction. The __TSC2__ gene product, tuberin, encodes a GTPase‐activating protein (GAP) domain, which regulates the activ