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The diagnostic significance of Myf-3 hypermethylation in malignant lymphoproliferative disorders

โœ Scribed by Taylor, JME; Kay, PH; Spagnolo, DV

Book ID
110054851
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
164 KB
Volume
15
Category
Article
ISSN
0887-6924

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Myf-3 is the human homologue of the murine Myo-D1 gene involved in muscle-cell differentiation. Using Southern blot analysis, we examined methylation of Myf-3 in histologically normal colonic mucosae, adenomas and carcinomas from a large series of patients with primary colorectal cancer. Hypermethyl