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The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila

✍ Scribed by Kirst King-Jones; Michael A. Horner; Geanette Lam; Carl S. Thummel


Book ID
116372478
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
435 KB
Volume
4
Category
Article
ISSN
1550-4131

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Orphan nuclear receptor binding site in
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## Abstract Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are members of the nuclear receptor superfamily that regulate target gene transcription in a ligand‐dependent manner. CAR and PXR have a rather broad, overlapping set of ligands that range from natural steroids to xeno