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The dexamethasone suppression test as a predictor of response to desipramine

โœ Scribed by Robert J. Bielski; Charles L. West; Christine L. Shafer; Gregory H. Holmes

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
369 KB
Volume
2
Category
Article
ISSN
0885-6222

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โœฆ Synopsis

Thirty-four endogenously depressed outpatients were treated with desipramine following dexamethasone suppression tests (DSTs). When mean change scores on the Hamilton scale were compared between DST-suppressors and non-suppressors there was a clear trend toward more favourable response in the non-suppressors. However, this finding fell just short of reaching statistical significance. Ten out of 13 DST-non-suppressors (77 per cent) responded to desipramine, while 10 out of 21 suppressors (48 per cent) responded. This difference was not significant.

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