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The Development of β-Lactam Antibiotics in Response to the Evolution of β-Lactamases

✍ Scribed by Sabiha Y. Essack

Book ID
110310106
Publisher
Springer US
Year
2001
Tongue
English
Weight
127 KB
Volume
18
Category
Article
ISSN
0724-8741

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✍ T. K. Vasudevan; V. S. R. Rao 📂 Article 📅 1981 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 609 KB

## Abstract Conformational‐energy calculations were carried out on the new family of β‐lactam antibiotics (viz., thienamycin, PS‐5, 1‐oxa‐ and 1‐thiapenems, and their close analogs); these exhibit broad‐spectrum antibacterial activity and stability towards β‐lactamase‐producing strains. The bicycli