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The development of the cerebral cortex

โœ Scribed by Mellus, E. Lindon


Publisher
Wiley (John Wiley & Sons)
Year
1912
Tongue
English
Weight
650 KB
Volume
14
Category
Article
ISSN
0002-9106

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โœฆ Synopsis


During the course of an investigation (still incomplete) of the so-ca,lled 'motor area' in man (anterior central convolution of the cerebral cortex) I had occasion to examine sectioqs from that area in the brain of an eight months foetus. To my surprise I found the corona radiata of both central convolutions thickly sown with what appeared to be migrating cells. These cells were in various stages of development, the large majority resembling the neuroblasts just leaving the matrix in e$rlier stages, but many were well advanced in development, the nucleus having a distinct nucleolus and being enveloped by a considerable cell body, This cell body was either round or ovoid. Many of the latter forln had a distinct apical process at one or the other extremity, this being sometimes directed toward the cortex, at other times away from it as if the nucleus were being propelled so rapidly that the enveloping protoplasm was inclined to drag behind. The long diameter of the ovoid cells seemed always to indicate the direction of the movement, some of those quite near the cortex of the fissure walls having apparently turned toward the cortex and in such the long diameter was at an acute or almost right an.gle to that of those more toward the center of the corona radiata. The granules or undeveloped nuclei scattered through the corona radiata were of two sorts, and sizes. The smaller about 5 micra in diameter stained deeply and showed no nucleolus, the others about 10 micra in diameter were faintly stained and contained two or more dark spots. At first I was inclined tolook upon the smaller of these two granules as spongioblasts and the paler as neuroblasts, but I found as many of the latter as the former in the first (molecular) layer of the cortex. In this por-


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