The development of spontaneous metastases after the removal of a “primary” tumor II. Standardization protocol of 5 animal tumors

Vascular density in colorectal liver met

Vascular density in colorectal liver metastases increases after removal of the primary tumor in human cancer patients

✍ Charlotte F.J.M. Peeters; Johan R. Westphal; Robert M.W. de Waal; Dirk J. Ruiter 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 625 KB

## Abstract In animal models, explosive growth of metastases after removal of the primary tumor has been attributed to abolishment of angiogenesis inhibition. We investigated the influence of (removal of) the primary tumor on vascularization of liver metastases in human colorectal cancer patients.

Induction of pulmonary metastases in bot

Induction of pulmonary metastases in both immune and nonimmune mice: Effect of the removal of a transplanted primary tumor

✍ Hilda Wexler; Paul B. Chretien; Alfred S. Ketcham; William F. Sindelar 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 550 KB

## Abstract In mice bearing a benzypyrene‐induced fibrosarcoma tumor, the survival was determined of intravenously injected tumor cells at various intervals after previous immunization of experimental animals by induction and subsequent excision of a transplanted primary tumor in the soft tissues o

Induction of pulmonary metastases in bot

Induction of pulmonary metastases in both immune and nonimmune mice: Effect of the removal of a transplanted primary tumor

✍ Hilda Wexler; Paul B. Chretien; Alfred S. Ketcham; William F. Sindelar 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 550 KB

## Abstract In mice bearing a benzypyrene‐induced fibrosarcoma tumor, the survival was determined of intravenously injected tumor cells at various intervals after previous immunization of experimental animals by induction and subsequent excision of a transplanted primary tumor in the soft tissues o

Outgrowth of human liver metastases afte

Outgrowth of human liver metastases after resection of the primary colorectal tumor: A shift in the balance between apoptosis and proliferation

✍ Charlotte F.J.M. Peeters; Robert M.W. de Waal; Theo Wobbes; Johan R. Westphal; T 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 232 KB

## Abstract Rapid outgrowth of metastases after removal of the primary tumor has been described in several mouse models. Loss of primary tumor‐induced inhibition of angiogenesis in the metastases has been suggested as the underlying cause. Accordingly, we recently demonstrated that vascular density

Risk factors for the development of seco

Risk factors for the development of second primary tumors among men after laryngeal and hypopharyngeal carcinoma : A multicentric European study

✍ Rajesh P. Dikshit; Paolo Boffetta; Christine Bouchardy; Franco Merletti; Paolo C 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 91 KB 👁 2 views

## Abstract ## BACKGROUND Second primary tumors (SPT) constitute a major threat to the survival of patients with laryngeal carcinoma. However, to the authors' knowledge little is known regarding the risk factors for developing SPTs or about the strategy to be followed to avoid them. ## METHODS E

Rodent model of systemic mammary tumor d

Rodent model of systemic mammary tumor disease by surgical removal of the spontaneously metastasizing SMT2A mammary carcinoma: Inhibitory effect of the stable prostacyclin Analogue cicaprost on occult metastasis

✍ Michael Schirner; Martin R. Schneider 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 575 KB