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The Development of Recombinant Human Serum Albumin

โœ Scribed by Kaoru Kobayashi; Norifumi Nakamura; Akinori Sumi; Takao Ohmura; Kazumasa Yokoyama


Book ID
111333733
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
656 KB
Volume
2
Category
Article
ISSN
1091-6660

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The objective was to evaluate the impact of pH and NaCl content on aggregation, particle formation, and solubility of a hydrophobic recombinant human cytokine in formulations with human serum albumin (HSA) as stabilizing excipient. While cytokine-HSA formulations were stable at physiological pH, a t