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The development of potential new fluorine-18 labelled radiotracers for imaging the GABAA receptor

✍ Scribed by Jackson, Alexander; Guilbert, Benedicte B.; Plant, Stuart D.; Goggi, Julian; Battle, Mark R.; Woodcraft, John L.; Gaeta, Alessandra; Jones, Clare L.; Bouvet, Denis R.; Jones, Paul A.; O’Shea, Dennis M.; Zheng, Penny Hao; Brown, Samantha L.; Ewan, Amanda L.; Trigg, William

Book ID: 118233147
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 996 KB
Volume: 23
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2012.11.066

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## Abstract The involvement of gamma amino butyric acid (GABA) receptors in a variety of neurological and psychiatric diseases has promoted the development and use of radiolabelled benzodiazepines (BZ) for brain imaging by PET. However, these radioligands are unable to distinguish between the vario