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The development of oral vaccines based on live attenuated Salmonella strains

โœ Scribed by S. Chatfield; M. Roberts; P. Londono; I. Cropley; G. Douce; G. Dougan

Book ID
109306881
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
559 KB
Volume
7
Category
Article
ISSN
0928-8244

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A procedure to attenuate live influenza virus of type A and type B was developed using adaptation of the virus to grow at 25 degrees C (cold adaptation; ca). Through a series of stepwise passages, two stable mutants were obtained and designated as 'Master' strains, one for type A influenza virus (A/