The Development of New Isoxazolone Based Inhibitors of Tumor Necrosis Factor-Alpha (TNF-α) Production.
✍ Scribed by Michael P. Clark; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 32 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The preparation of 2‐penten‐1‐yl and 3‐methyl‐2‐buten‐1‐yl derivatives of adenine 2a,b, 7‐deazaadenine 2c,d, 2‐aminopurine 4a,b and 5a,b, 4‐aminopyrazolo[3,4‐__d__]pyrimidine 7a,b and 7‐amino‐v‐triazolo‐[4,5‐__d__]pyrimidine 8a–10a and 8b‐10b is described. The synthesis of compounds 2a‐
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