The development of chick-embryo-lethal-orphan (CELO) virus T and V antigens in lytically infected chick kidney cells
✍ Scribed by Jeffrey Anderson; Kenneth J. McCormick; Wayne A. Stenback; John J. Trentin
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- French
- Weight
- 434 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
The sequential development of the CELO‐specific T and virion antigens was studied in lytically infected chick kidney cells using the indirect immunofluorescence technique. The T antigen was detected 6 hours after infection, and rapidly increased until a peak was reached at 20–24 h. The V antigen could not be detected until 20 h after infection. The V antigen, but not the T antigen, was inhibited by cytosine arabinoside. Both antigens were inhibited by cycloheximide. After storage in liquid nitrogen for 3 weeks, the T antigen in fixed cells could not be detected by indirect immunofluorescence tests.