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The development and function of regulatory T cells

✍ Scribed by Creg J. Workman; Andrea L. Szymczak-Workman; Lauren W. Collison; Meenu R. Pillai; Dario A. A. Vignali

Publisher: Springer
Year: 2009
Tongue: English
Weight: 450 KB
Volume: 66
Category: Article
ISSN: 1420-682X
DOI: 10.1007/s00018-009-0026-2

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## Abstract Adult T‐cell leukemia/lymphoma (ATLL) patients are highly immunocompromised, but the underlying mechanism responsible for this state remains obscure. Recent studies demonstrated that __FOXP3__, which is a master control gene of naturally occurring regulatory T (Treg) cells, is expressed