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The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

โœ Scribed by Stevenson, Lauren F; Sparks, Alison; Allende-Vega, Nerea; Xirodimas, Dimitris P; Lane, David P; Saville, Mark K

Book ID
110031945
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
467 KB
Volume
26
Category
Article
ISSN
0261-4189

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โœ Weisi Wang; Yongzhou Hu ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 494 KB

## Abstract The powerful tumor suppressor p53 takes charge of a regulatory network to guard over the living cells from harmful effect of different forms of stress and eradicate the tumor cells for normal physiological condition maintenance. However the antitumor function of p53 is often attenuated