Microchip-ESI-MS determination of dissoc
โ
Jaroslava Svobodovรก; Sonal Mathur; Alexander Muck; Thomas Letzel; Aleลก Svatoลก
๐
Article
๐
2010
๐
John Wiley and Sons
๐
English
โ 246 KB
## Abstract An onโline microfluidic system for determination of dissociation constants of enzyme/substrate weak interactions by nanoESIโMS is introduced. The microchip was designed to permit the enzyme and the substrate to mix by molecular diffusion in a pressureโdriven laminar flow. Introduction o