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The determination of acetaldehyde in human blood by the perchloric acid precipitation method: The characterization and elimination of artefactual acetaldehyde formation

✍ Scribed by C.J.Peter Eriksson; Yasuhiko Mizoi; Tatsushige Fukunaga

Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
310 KB
Volume
125
Category
Article
ISSN
0003-2697

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✦ Synopsis

An improved method for treating human blood samples taken for acetaldehyde analysis is presented. The protein precipitation is performed by instant and thorough mixing of the blood sample in a saline solution of perchloric acid. This procedure effectively reduces the artefactual formation of acetaldehyde that occurs during the protein precipitation. The remaining artefactual acetaldehyde, which is mainly formed during the incubation prior to head-space analysis, can be corrected for by a correction curve made using control blood to which ethanol has been added.

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