The detection of prostatic carcinoma

✍ Scribed by R. Vleeming; J. W. Noordzij; Th. M. Reijke; K. H. Kurth

• Publisher: Springer-Verlag
• Year: 1993
• Tongue: English
• Weight: 664 KB
• Volume: 11
• Category: Article
• ISSN: 0724-4983
• DOI: 10.1007/bf00182174

✦ Synopsis

In this prospective study a comparison of 4versus 7-MHz transrectal ultrasonography for the detection of prostatic carcinoma is reported. A total of 150 prostates were biopsied due to suspicion of malignancy arising at either digital rectal examination, 4-and/or 7-MHz transrectal ultrasonography, or elevated serum prostate-specific antigen levels. Malignancies of the prostate were detected in 68 of the 147 eligible biopsy core specimens. The results show only marginal differences in the sensitivity, specificity, and predictive values for the two transducers.

(PSA), and 4-and 7-MHz TRUS in the same session. All patients were referred because of suspected carcinoma at rectal examination, due to elevated PSA values, or for determination of the volume of a tactile benign prostatic enlargement (Table 1). Patients with fixed tumor or tumor invading adjacent structures (T4 tumors) were not considered in this study. Transrectal ultrasonography was performed using Bruel & Kjaer equipment (type 1846) in combination with a 4-MHz transaxial scanner (type 1850; focus, 30-70 mm) or a 7-MHz multiplane scanner (type 8551, focus 10-60mm). In all patients, ultrasonographically guided core specimens were obtained by the transrectal route from echopenic areas and from suspected areas on DRE. In patients showing an elevated PSA level without suspicion on DRE or TRUS, one to two random biopsies of the prostate were taken bilaterally.