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The design of peptide analogues for improved absorption

โœ Scribed by David Barlow; Takashi Satoh


Book ID
113275714
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
874 KB
Volume
29
Category
Article
ISSN
0168-3659

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Prodrugs of nucleoside analogues for imp
โœ Fujun Li; Hans Maag; Tom Alfredson ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 301 KB

Nucleoside analogues are widely used for the treatment of antiviral infections and anticancer chemotherapy. However, many nucleoside analogues suffer from poor oral bioavailability due to their high polarity and low intestinal permeability. In order to improve oral absorption of these polar drugs, p