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The design and synthesis of β-trifluoromethylenol phosphates as potential insecticides

✍ Scribed by Yixiang Ding; Xiaogen Huang


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
79 KB
Volume
14
Category
Article
ISSN
1042-7163

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✦ Synopsis


Abstract

A new group of compounds, β‐trifluoromethylenol phosphates [(RO)~2~P(O)OCRCHCF~3~], has been designed and prepared by several methods. Some of them showed good insecticidal activities. In the molecular structure, the designed leaving group can rearrange to a powerful electrophilic agent, β,β‐difluorovinyl ketone, which would be a potential enzyme inhibitor. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:304–308, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10147


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