Mathematical model for the optimization
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M. A. Martin; G. Frutos; B. Del Castillo; J. Alvarez-Builla; P. J. Martin
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Article
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1992
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John Wiley and Sons
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English
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A number of nucleophiles have been successfully identified and quantified using the Krohnke reaction with 2,3,-diphenyl derivatives of quinolizinium salts. Optimization of the reaction conditions by means of a mathematical model involving analysis of the response surface has led to a better understa