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The deletion genotype of the angiotensin I-converting enzyme is associated with an increased vascular reactivity in vivo and in vitro

✍ Scribed by Daniel Henrion; Joelle Benessiano; Ivan Philip; Sandrine Vuillaumier-Barrot; Marc Iglarz; Gaetan Plantefève; Didier Chatel; Ulrich Hvass; Geneviève Durand; Jean-Marie Desmonts; Philippe Amouyel; Bernard I Lévy


Book ID
119550759
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
190 KB
Volume
34
Category
Article
ISSN
1558-3597

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An insertion(I)/deletion(D) polymorphism in the angiotensin I-converting enzyme (ACE) gene seems to be associated with clinical heart disease in patients with diabetes mellitus. It is not known whether increased atherosclerosis or other factors among individuals with certain ACE-gene subtypes form t