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The decoupling between genetic structure and metabolic phenotypes in Escherichia coli leads to continuous phenotypic diversity

✍ Scribed by V. SABARLY; O. BOUVET; J. GLODT; O. CLERMONT; D. SKURNIK; L. DIANCOURT; D. De VIENNE; E. DENAMUR; C. DILLMANN

Book ID: 110912180
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 573 KB
Volume: 24
Category: Article
ISSN: 1010-061X
DOI: 10.1111/j.1420-9101.2011.02287.x

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Mutants of Escherichia coli have been isolated containing streptomycin suppressors that exhibit novel phenotypes with respect to strA alleles. In one class of these mutants, the suppressor effect parallels a strong binding to the ribosome of an additional protein in at least stoichiometric amounts.