The dancing larynx—a variant of palatal tremor?

✍ Scribed by Anette Schrag; Kailash P. Bhatia; Niall P. Quinn; C. David Marsden

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 239 KB
• Volume: 14
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/1531-8257(199909)14:5<882::aid-mds1032>3.0.co;2-5

✦ Synopsis

The so-called atypical neuroleptics represent a new class of antipsychotic drugs that only rarely cause extrapyramidal side effects. Therefore, they have proved valuable not only for the treatment of schizophrenia, but also for drug-induced psychosis in parkinsonian patients. 1 Unfortunately, the use of clozapine, the first atypical neuroleptic, has been limited by agranulocytosis that occurs in approximately 0.6% of patients. 2 In contrast, the new substance olanzapine has not been related to hematologic adverse events in any of the 2500 patients who were evaluated in five large clinical trials. 3 Recently, however, prolongation of clozapineinduced leucopenia has been reported in three patients who received olanzapine immediately after clozapine had been discontinued. 4 We report on two patients who developed reversible leucopenia while being treated with olanzapine.