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The D3-receptor agonist (±)-7-hydroxy-N,N-di-n-propyl-2-aminotetralin (7-OH-DPAT) attenuates morphine-induced hyperlocomotion in mice

✍ Scribed by Suzuki, Tsutomu; Maeda, Jun; Funada, Masahiko; Misawa, Miwa


Book ID
121919350
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
350 KB
Volume
187
Category
Article
ISSN
0304-3940

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✍ Makoto Ukai; Hiroko Tamoto; Tomoko Tanaka; Tsutomu Kameyama 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB 👁 2 views

The present study was designed to characterize the dopamine D 3 receptor agonist R()-7-hydroxy-N,N-di-n-propyl-2-aminotetralin (R()-7-OH-DPAT)-induced changes in locomotor activity in mice. Although R()-7-OH-DPAT (0 . 01±10 mg/kg) produced a signi®cant decrease in horizontal and vertical motility wi