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The Cytotoxicity of 2-Formyl and 2-Acetyl-(6-picolyl)-4N-Substituted Thiosemicarbazones and Their Copper(II) Complexes

✍ Scribed by Merrill C. Miller; III; Kenneth F. Bastow; Christa N. Stineman; John R. Vance; Sun C. Song; Douglas X. West; Iris H. Hall


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
543 KB
Volume
331
Category
Article
ISSN
0365-6233

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πŸ“œ SIMILAR VOLUMES


Multiple mechanisms for cytotoxicity ind
✍ M. C. Miller III; C. N. Stineman; J. R. Vance; D. X. West; I. H. Hall πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 259 KB

The purpose of this study was to evaluate the mechanism by which 2-acetylpyrazine-4 N-substituted thiosemicarbazone copper II complexes mediate their cytotoxicity. These compounds were shown to be cytotoxic to a variety of human and rodent tumors in cell culture and are potent cytocidal agents as de