The cytomegalovirus ppUL83 protein contains an immunodominant A\*0201 restricted epitope between residues 495 and 503. We investigated the tolerance of this epitope to sequence variation in the context of peptide binding to HLA A\*0201 and the ability to induce an Interferon gamma (IFNgamma) respons
β¦ LIBER β¦
The cytotoxic T cell response to peptide analogs of the HLA-A*0201-restricted MUC1 signal sequence epitope, M1.2
β Scribed by Malcolm S. Mitchell; Teri A. Lund; Andrew K. Sewell; Francesco M. Marincola; Elyse Paul; Kim Schroder; Darcy B. Wilson; June Kan-Mitchell
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 861 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0340-7004
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## Abstract The epithelial mucin MUC1 is one of the few tumourβassociated antigens identified for breast cancer. Several MUC1βderived peptides binding HLAβA\*0201 molecules have been identified that correspond to sequences outside the tandem repeat. Immunisation with some of these peptides induces
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