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The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis

✍ Scribed by Xiaojuan Wang; Shaoxi Liao; Erik R. Nelson; Robert Schmalzigaug; Robert F. Spurney; Farshid Guilak; Richard T. Premont; Diane Gesty-Palmer


Book ID
116303802
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
731 KB
Volume
425
Category
Article
ISSN
0006-291X

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## Abstract AMP‐activated protein kinase (AMPK) is an energy‐sensing kinase that has recently been shown to regulate the differentiation of preadipocytes and osteoblasts. However, the role of AMPK in stem cell differentiation is largely unknown. Using in vitro culture models, the present study demo